Motilium (domperidone): what it does and when people use it

Motilium, the brand name for domperidone, is a medicine many people use to relieve nausea, vomiting, bloating and slow stomach emptying. It works by speeding up stomach movement and can also increase breast milk in some women. That makes it useful in a few different situations — but it also comes with important safety flags you should know before taking it.

How Motilium is used — practical facts

Doctors commonly prescribe Motilium for short-term nausea after stomach upset, migraines, or side effects from other medicines. A common adult approach is to take it before meals to help the stomach empty faster. Don’t treat that as a dose sheet — follow the exact instructions your prescriber gives and the patient leaflet that comes with the box.

Some people use domperidone off-label to boost milk supply. Evidence shows it can raise prolactin and help with lactation, but that decision should be made with a doctor because of the possible risks.

What to watch for and safety tips

The biggest safety concern with Motilium is its effect on the heart. Domperidone can change the heart’s electrical rhythm (QT prolongation) and increase the chance of irregular heartbeat, especially in older adults or when combined with other QT‑affecting drugs. Tell your doctor about any heart disease, low potassium, or medicines such as some antibiotics, antifungals, antiarrhythmics, or certain antidepressants before starting Motilium.

Common side effects include dry mouth, abdominal cramping, and headache. Serious symptoms to seek immediate care for include fainting, severe palpitations, shortness of breath, or chest pain. If you’re pregnant or breastfeeding, talk openly with your clinician — domperidone decisions depend on the situation and alternatives.

Don’t buy Motilium from unverified online sellers. Use licensed pharmacies, keep prescriptions current, and check packaging for authenticity. If you notice spelling errors on leaflets or suspicious pricing, stop and contact a pharmacist or the site’s customer service.

Alternatives and next steps

If Motilium isn’t right for you, doctors may recommend other options like metoclopramide, ondansetron, or non-drug approaches such as small frequent meals, ginger, or changing other medications that cause nausea. Each alternative has its own benefits and risks — for example, metoclopramide can cause movement-related side effects and is usually short-term.

Bottom line: Motilium can work well for nausea and delayed stomach emptying, but it isn’t risk-free. Ask your prescriber about heart checks, drug interactions, and the shortest effective duration. If you want more reading, our site has related articles on nausea treatments, medication safety, and how to find reputable pharmacies.

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